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effect of external apple vinegar application on varicosity symptoms, pain, and social appearance anxiety: a randomized controlled trial. Evid Based Complement Alternat Med. 2016;2016:6473678. https://pubmed.ncbi.nlm.nih.gov/26881006/

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Montgomery L, Seys J, Mees J. To pee, or not to pee: a review on envenomation and treatment in European jellyfish species. Mar Drugs. 2016;14(7):127. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962017/

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Wilcox CL, Headlam JL, Doyle TK, Yanagihara AA. Assessing the efficacy of first-aid measures in Physalia sp. Envenomation, using solution– and blood agarose-based models. Toxins (Basel). 2017;9(5):149. https://pubmed.ncbi.nlm.nih.gov/28445412/

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Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5 %] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634–9. https://pubmed.ncbi.nlm.nih.gov/31328306/

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Feldstein S, Afshar M, Krakowski AC. Chemical burn from vinegar following an internet-based protocol for self-removal of nevi. J Clin Aesthet Dermatol. 2015;8(6):50. https://pubmed.ncbi.nlm.nih.gov/26155328/

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Kroeger CM, Brown AW, Allison DB. Differences in Nominal Significance (DINS) Error leads to invalid conclusions: letter regarding, “Diet enriched with fresh coconut decreases blood glucose levels and body weight in normal adults.” J Complement Integr Med. 2019;16(2):/j/jcim.2019.16.issue-2/jcim-2018–0037/jcim-2018–0037.xml. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957306/

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Richardson JB, Dixon M. Varicose veins in tropical Africa. Lancet. 1977;1(8015):791–2. https://pubmed.ncbi.nlm.nih.gov/66583/

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O’Keefe SJD, Chung D, Mahmoud N, et al. Why do African Americans get more colon cancer than Native Africans? J Nutr. 2007;137(1 Suppl):175S-82S. https://pubmed.ncbi.nlm.nih.gov/17182822/

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Tuohy KM, Gougoulias C, Shen Q, Walton G, Fava F, Ramnani P. Studying the human gut microbiota in the trans-omics era – focus on metagenomics and metabonomics. Curr Pharm Des. 2009;15(13):1415–27. https://pubmed.ncbi.nlm.nih.gov/19442166/

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Burkitt DP. Two blind spots in medical knowledge. Nurs Times. 1976;72(1):24–7. https://pubmed.ncbi.nlm.nih.gov/54904/

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Crowe FL, Appleby PN, Allen NE, Key TJ. Diet and risk of diverticular disease in Oxford cohort of European Prospective Investigation into Cancer and Nutrition (EPIC): prospective study of British vegetarians and non-vegetarians. BMJ. 2011;343:d4131. https://pubmed.ncbi.nlm.nih.gov/21771850/

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Knutsen SF. Lifestyle and the use of health services. Am J Clin Nutr. 1994;59(5 Suppl):1171S-5S. https://pubmed.ncbi.nlm.nih.gov/8172119/

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Eddy TP, Taylor GF. Sublingual varicosities and vitamin C in elderly vegetarians. Age Ageing. 1977;6(1):6–13. https://pubmed.ncbi.nlm.nih.gov/842407/

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Reinecke JK, Hinshaw MA. Nail health in women. Int J Womens Dermatol. 2020;6(2):73–9. https://pubmed.ncbi.nlm.nih.gov/32258335/

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Halteh P, Scher RK, Lipner SR. Over-the-counter and natural remedies for onychomycosis: do they really work? Cutis. 2016;98(5):E16–25. https://pubmed.ncbi.nlm.nih.gov/28040821/

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Halteh P, Scher RK, Lipner SR. Over-the-counter and natural remedies for onychomycosis: do they really work? Cutis. 2016;98(5):E16–25. https://pubmed.ncbi.nlm.nih.gov/28040821/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Iorizzo M. Tips to treat the 5 most common nail disorders: brittle nails, onycholysis, paronychia, psoriasis, onychomycosis. Dermatol Clin. 2015;33(2):175–83. https://pubmed.ncbi.nlm.nih.gov/25828710/

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Maddy AJ, Tosti A. Hair and nail diseases in the mature patient. Clin Dermatol. 2018;36(2):159–66. https://pubmed.ncbi.nlm.nih.gov/29566920/

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Iorizzo M. Tips to treat the 5 most common nail disorders: brittle nails, onycholysis, paronychia, psoriasis, onychomycosis. Dermatol Clin. 2015;33(2):175–83. https://pubmed.ncbi.nlm.nih.gov/25828710/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Gupta AK, Konnikov N, Lynde CW. Single-blind, randomized, prospective study on terbinafine and itraconazole for treatment of dermatophyte toenail onychomycosis in the elderly. J Am Acad Dermatol. 2001;44(3):479–84. https://pubmed.ncbi.nlm.nih.gov/11209118/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Gupta AK, Daigle D, Foley KA. Network meta-analysis of onychomycosis treatments. Skin Appendage Disord. 2015;1(2):74–81. https://pubmed.ncbi.nlm.nih.gov/27170937/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Iorizzo M. Tips to treat the 5 most common nail disorders: brittle nails, onycholysis, paronychia, psoriasis, onychomycosis. Dermatol Clin. 2015;33(2):175–83. https://pubmed.ncbi.nlm.nih.gov/25828710/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Sleven R, Lanckacker E, Delputte P, Maes L, Cos P. Evaluation of topical antifungal products in an in vitro onychomycosis model. Mycoses. 2016;59(5):327–30. https://pubmed.ncbi.nlm.nih.gov/26857689/

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Kelly S, Liu D, Wang T, Rajpara A, Franano C, Aires D. Vinegar sock soak for tinea pedis or onychomycosis. J Am Acad Dermatol. Published online September 22, 2017:S0190–9622(17)32448–9.; https://pubmed.ncbi.nlm.nih.gov/28947288/

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Satchell AC, Saurajen A, Bell C, Barnetson RSC. Treatment of dandruff with 5 % tea tree oil shampoo. J Am Acad Dermatol. 2002;47(6):852–5. https://pubmed.ncbi.nlm.nih.gov/12451368/

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Satchell AC, Saurajen A, Bell C, Barnetson RSC. Treatment of interdigital tinea pedis with 25 % and 50 % tea tree oil solution: a randomized, placebo-controlled, blinded study. Australas J Dermatol. 2002;43(3):175–8. https://pubmed.ncbi.nlm.nih.gov/12121393/

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Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Fam Pract. 1994;38(6):601–5. https://pubmed.ncbi.nlm.nih.gov/8195735/

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Murdan S. Nail disorders in older people, and aspects of their pharmaceutical treatment. Int J Pharm. 2016;512(2):405–11. https://pubmed.ncbi.nlm.nih.gov/27180233/

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Maddy AJ, Tosti A. Hair and nail diseases in the mature patient. Clin Dermatol. 2018;36(2):159–66. https://pubmed.ncbi.nlm.nih.gov/29566920/

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Ingrown toenails. American Academy of Family Physicians. https://www.aafp.org/dam/brand/aafp/pubs/afp/issues/2019/0801/p158-s1.pdf. Updated August